The 75g oral glucose tolerance test (OGTT) is a diagnostic test that evaluates how efficiently the body processes glucose. After an overnight fast, a person consumes a drink containing 75 grams of glucose, and blood samples are taken at set intervals — most commonly after two hours.
When capillary whole blood is used (e.g., from a finger prick), the glucose concentration reflects the body’s ability to clear sugar from the bloodstream under real-world conditions. This measurement helps identify type 2 diabetes, impaired glucose tolerance (prediabetes), and is critical in screening for gestational diabetes during pregnancy. The two-hour value is often the most informative, as it indicates whether blood sugar returns to normal after a glucose challenge.